Chronic fatigue syndrome is disorder generally related with the long periods of extreme tiredness and weakness. There is no absolute treatment available for this syndrome. Only some of the affected persons recover their full health. There are no drugs available only for the chronic fatigue syndrome. Doctors generally use various drugs to control different symptoms of chronic fatigue syndrome. Some of the drugs are listed below.

Amitriptyline: this drug is generally used as a treatment to depression. That is why, this drug is used to decrease the symptoms of anxiety and depression in the chronic fatigue syndrome affected persons.

Imipramine: this drug is also used in conjunction with psychotherapy to treat of various forms of depression. There are some side effects of this drug. This drug can cause some allergic reaction and may affect blood pressure.

Doxepin: this drug is to treat anxiety disorders. It is also used as pain killer for certain chronic and neuropathic pain. This drug should be used with caution to the patients with cardiovascular disease, hyperthyroidism and seizure disorders.

Desipramine: this drug is often used to treat depression. This drug is also used as analgesic adjunct in chronic pain. This drug should not be discontinued abruptly to persons receiving long-term high-dose therapy.

Clomipramine: Coenzyme Q10, Vitamin B2 is the nutrients depleted in this drug. It is used to treat obsessive-complusive disorder (OCD). This drug is used to relieve depression, panic attacks, and chronic pain. Pregnancy risk factors are related with the use of this drug.

Nortriptyline: it is an antidepressant drug. The effect of this drug can be seen for 2 or more weeks after initiation of therapy. Avoid use of Nortriptyline during pregnancy and lactation.

Nonsteroidal: it is an Anti-Inflammatory Drugs. This drug is used for the management of inflammatory and rheumatoid disorders. These inflammatory and rheumatoid disorders such as spondylitis, mild to moderate pain, fever, dysmenorrhea, and acute migraine headache are very common in chronic fatigue syndrome.

All of these above drugs are used to treat chronic fatigue syndrome, but none of these drugs are considered safe. These drugs are used because there is no alternative therapy available against chronic fatigue syndrome.